With a trip to Wembley on the line, Portsmouth welcome Exeter City to Fratton Park in the semi-finals of the Checkatrade Trophy. Pompey are the competition's reigning champions.
Atletico Madrid host Liverpool in the Champions League Round of 16 at Wanda Metropolitano Stadium. Liverpool have always progressed against Spanish teams in a two-legged UCL tie.
Borussia Dortmund welcome former manager Thomas Tuchel and his PSG side to Signal Iduna Park for their UEFA Champions League Round of 16 first leg.
Newport County take on Salford City in the second semi-final from the Checkatrade Trophy
Tottenham host RB Leipzig in the first leg of their Champions League Round of 16 tie. The Tottenham Hotspur Stadium has seen more goals than any other venue in this season's UCL.
Atalanta face Valencia in the first leg of their UEFA Champions League Round of 16 tie at the San Siro. This will be the first ever encounter between the two sides.
Derby County welcome Fulham to Pride Park in the Sky Bet Championship.
St. Mirren host Hearts at St. Mirren Stadium in the Ladbrokes Scottish Premiership.
Chelsea and Tottenham go head-to-head in the Premier League as they meet at Stamford Bridge.
Thomas Frank's promotion-chasing Brentford welcome Blackburn to Griffin Park in the Sky Bet Championship. Bradley Dack struck early on to help Rovers to a 1-0 win in the reverse game.
Steven Gerrard's Rangers travel to take on St Johnstone at McDiarmid Park in the SPFL Ladbrokes Premiership. Rangers won 4-0 on their first visit here earlier this season.
Sutton United host Barrow in the Vanarama National League at Borough Sports Ground.
Brendan Rodgers's Leicester City welcome Premier League champions Manchester City to the King Power Stadium. Pep Guardiola's side ran out 3-1 winners when the sides met earlier this season.
Mikel Arteta's Arsenal welcome another of his former clubs - Everton - to the Emirates Stadium in the Premier League. A tightly fought reverse fixture at Goodison ended 0-0.